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Covid Vaccine

Good news within.

‘Humanized’ mice provide clue to why COVID hits some harder than others​


NEW HAVEN, Conn. — What causes COVID-19 to be mild for some but deadly to others? A new study finds the body’s own antiviral inflammatory response to COVID may reveal a clue.

Estimates show that about 80 to 90 percent of people with COVID-19 only experience mild symptoms — or no symptoms at all. However, the other 10 and 20 percent develop much more severe symptoms, with over 800,000 Americans dying of the illness so far. The exact reason for this phenomenon has largely remained a mystery.

Now, an experiment by Yale researchers on “humanized mice” — rodents especially engineered to boast human-like immune systems — reveals a link between severe COVID-19 symptoms and the inflammatory response to infection. The study also suggests two therapies, monoclonal antibodies and the steroid dexamethasone, can be effective against COVID-19 depending on time of treatment. Study authors note that patients should receive antibodies early on in an infection while the steroids are only effective (and safe) as a later stage approach.

This study’s unique use of rodents with humanized immune systems allowed scientists to document just how differently the human immune system reacts to COVID-19.

“If you infect a standard laboratory mouse with SARS-CoV-2 they will get infected, but not get seriously ill,” says senior study author Richard Flavell, Sterling Professor of Immunobiology at Yale, in a university release. “But our humanized mice get sick and just don’t get better. Their whole immune system is on fire.”

Antibodies early and steroids late may be the magic formula​

The coronavirus samples infecting the humanized mice came directly from seriously ill human patients. Researchers then tracked the health outcomes of the mice.

The mice developed symptoms and issues consistent with those observed among serious human COVID-19 patients, such as lung damage, weight loss, and a constant heightened inflammatory response — eventually leading to tissue damage.

Administering monoclonal antibodies just before or shortly after infection helped prevent symptoms. Any later, however, and the antibodies appeared largely ineffective. Conversely, while the steroid dexamethasone was actually fatal to the mice when given during early infection (due to suppressing the immune system), it proved helpful at fighting COVID-19 during the later stages of the disease via suppression of the inflammatory response that damages organs.

“Early in the course of disease, a strong immune response is crucial for survival,” concludes Esen Sefik, a Howard Hughes Medical Institute (HHMI) Fellow at the Damon Runyon Cancer Research Foundation. “Later in the disease, it can be fatal.”

Moving forward, study authors are also hopeful that further research with humanized mice will help answer some of the questions surrounding long COVID-19 symptoms.

The study is published in the journal Nature Biotechnology.
They gave my sister in law dexamethasone and Remdesivir. Saved her life.
 
So.....the first 3 jabs....don't work?

Do you actually realize when you argue against yourself? Or does it just happen by chance?
Well you see if the current variants have mutated past the simple antibodies the vaccines stimulate… then all the boosters won’t work… they will design a new vaccine with new boosters…

Now natural immunity or a vaccine based on the full virus might have more effective attributes against mutations, but all they are doing is giving tge same spike protein over and over and hoping the flood of antibodies will compensate… its going to have diminished returns each time
 
They gave my sister in law dexamethasone and Remdesivir. Saved her life.

Thank god they did. Regeneron, Dexamethasone, Remdesivir, Ivermectin, Monoclonal Antibodies (or Regeneron), megadose Vitamin C therapy etc., whatever works for a person to get them back to health - do it. The fact the Government and Pravda discount many of these therapeutic treatments (lack of money generated) is what's disgusting to me.

And again, if they're so worried about this pandemic ruining lives, they would have done everything in their power to shut down our borders. It's sickening.
 
With all due respect, Lebanon, why haven't you raised your voice more vehemently against those on the board - and there are many - who've incessantly downplayed the seriousness and actual risks posed by Covid?

I undertand you're not satisfied with the vaccinations, but you've also seemed to ignore those saying Covid is *nothing but the flu* and shouldn't be taken seriously to begin with.
vile Comrade Tibs, useful idiot,






Its the flu, bro.



Because you are unable to understand, and are quivering with fear that your masters implant so easily into you, you will continue your tirades and belittling of those with differing opinions.
You bigoted ********.
 
Thank god they did. Regeneron, Dexamethasone, Remdesivir, Ivermectin, Monoclonal Antibodies (or Regeneron), megadose Vitamin C therapy etc., whatever works for a person to get them back to health - do it. The fact the Government and Pravda discount many of these therapeutic treatments (lack of money generated) is what's disgusting to me.

And again, if they're so worried about this pandemic ruining lives, they would have done everything in their power to shut down our borders. It's sickening.
Remdisivir is an accepted and commonplace medication now for covid.. after all the bitching its the treatment they give you in the hospital… i had five to seven days of IV solutions of it.. kind of spaced near the end so I don’t know when they cut it off…
 
So i came here to post that i still haven’t been cleared to return to work… i have been totally covid free since the end of October… it took a little over a month for my blood to get back to acceptable levels from the internal bleeding,… i weaned myself off of oxygen as of two weeks ago because i had no interest in the three month program the hospital was planning…

I can drive.. i can pass all the standard tests, but they keep sending me for more precautionary tests despite no real cause for them… i mean its fine, but this is two solid weeks of them telling me they are worried about something then me getting a ton of tests that all come back negative…

The thing i really want to complain about is that they keep trying to put me on different blood pressure meds, and i swear i am following their instructions to the T and it is making my blood pressure, (which was to me totally acceptable…), climb.

its in the range my whole family is always in and we usually die in or around our 80’s if tge cancer doesn’t get us… last week my measurements were 127/76 they put me on another pill and now its 167/110…

Body chemistry is far from the sane for everyone… people react differently to various chemicals… just remember that as the mandates shove chemicals into you..
 
The mandates and fear mongering are purely political, and all coming from the left.
As you so often say, prove me wrong.
Scary stuff…


 
Last edited:
The mandates and fear mongering are purely political, and all coming from the left.
As you so often say, prove me wrong.
dRNSEf3.png


fMo7fg5.jpg
 
So i came here to post that i still haven’t been cleared to return to work… i have been totally covid free since the end of October… it took a little over a month for my blood to get back to acceptable levels from the internal bleeding,… i weaned myself off of oxygen as of two weeks ago because i had no interest in the three month program the hospital was planning…

I can drive.. i can pass all the standard tests, but they keep sending me for more precautionary tests despite no real cause for them… i mean its fine, but this is two solid weeks of them telling me they are worried about something then me getting a ton of tests that all come back negative…

The thing i really want to complain about is that they keep trying to put me on different blood pressure meds, and i swear i am following their instructions to the T and it is making my blood pressure, (which was to me totally acceptable…), climb.

its in the range my whole family is always in and we usually die in or around our 80’s if tge cancer doesn’t get us… last week my measurements were 127/76 they put me on another pill and now its 167/110…

Body chemistry is far from the sane for everyone… people react differently to various chemicals… just remember that as the mandates shove chemicals into you..
Make sure your job is paying you if you are in HC. Osha ETs mandates it regardless of where you got da Kung flu
 
vile Comrade Tibs, useful idiot,
Come-on man...I ain't believen you guys are still ****** with that troll. Even with all the hoopla after the election about closing them troll farms, y'all still feed the beast...lol

Troll farms reached 140 million Americans a month on Facebook before 2020 election, internal report shows​

In the run-up to the 2020 election, the most highly contested in US history, Facebook’s most popular pages for Christian and Black American content were being run by Eastern European troll farms. These pages were part of a larger network that collectively reached nearly half of all Americans, according to an internal company report, and achieved that reach not through user choice but primarily as a result of Facebook’s own platform design and engagement-hungry algorithm.

a7f6af757fabdc8f20258dd7cfe6e734.png
 
Scary stuff…


Sad that you feel we all need the approval (if fully vaccinated of course) of these ***-hats to gather at Christmas, but your avatar sig says it all.
 
called it in my sig line

Love owning you to this extent, that you even obsess over me with your sig line. Almost as cringy as Steelworth, Tim and Steeltime. Just can't keep me out of your heads. As the saying goes, I live there, rent free, 24/7. Damn, had no idea how deeply all this trauma has affected you. Hope things start looking up from here on. Life's too short to be this obsessed over a random stranger on a messageboard. Well, maybe not. Whatever turns you on, man. Yikes. Merry Christmas, Supe. 🤷‍♂️
 
1640184192650.png
 
Really wanna go there, Supe? LOL

'It's going to disappear': A timeline of Trump's claims that Covid-19 will vanish

You know, a lot of people think that goes away in April with the heat — as the heat comes in. Typically, that will go away in April.
President Trump February, 10 2020

China is working very, very hard. I have spoken to President Xi, and they’re working very hard. And if you know anything about him, I think he’ll be in pretty good shape. They’re — they’ve had a rough patch, and I think right now they have it — it looks like they’re getting it under control more and more. They’re getting it more and more under control. So I think that’s a problem that’s going to go away.
President Trump February 25, 2020

…when you have 15 people, and the 15 within a couple of days is going to be down to close to zero, that’s a pretty good job we’ve done.
President Trump February 26, 2020

It’s going to disappear. One day — it’s like a miracle — it will disappear. And from our shores, we — you know, it could get worse before it gets better. It could maybe go away. We’ll see what happens. Nobody really knows.
President Trump February 27, 2020

I don’t think people are panicking. I said last night — we did an interview on Fox last night, a town hall. I think it was very good. And I said, ‘Calm. You have to be calm.’ It’ll go away.
President Trump March 6, 2020

We’re prepared, and we’re doing a great job with it. And it will go away. Just stay calm. It will go away.
President Trump March 10, 2020

You know, we need a little a separation until such time as this goes away. It’s going to go away. It’s going to go away.
President Trump March 12, 2020

Stay calm. It will go away. You know it — you know it is going away, and it will go away. And we’re going to have a great victory.
President Trump March 30, 2020

It’s going to go away, hopefully at the end of the month. And, if not, hopefully it will be soon after that.
President Trump March 31, 2020

It is going to go away. It is going away.
President Trump April 3, 2020

It did go — it will go away.
President Trump April 7, 2020

But a lot of movement and a lot of progress has been made in a vaccine. But I think what happens is it’s going to go away. This is going to go away. And whether it comes back in a modified form in the fall, we’ll be able to handle it.
President Trump April 28, 2020

It’s going to go. It’s going to leave. It’s going to be gone. It’s going to be eradicated. And it might take longer. It might be in smaller sections. It’ll be — it won’t be what we had. And we also learned a lot.
President Trump April 29, 2020

And I think we’re doing very well on the vaccines but, with or without a vaccine, it’s going to pass, and we’re going to be back to normal.
President Trump May 5, 2020

Because, you know, this virus is going to disappear. It’s a question of when. Will it come back in a small way? Will it come back in a fairly large way? But we know how to deal with it now much better. You know, nobody knew anything about it, initially. Now we know we can put out fires.
President Trump May 6, 2020

Well, I feel about vaccines like I feel about tests. This is going to go away without a vaccine. It’s going to go away, and it’s — we’re not going to see it again, hopefully, after a period of time. You may have some — some flare-ups and I guess, you know, I would expect that. Sometime in the fall, you’ll have flare-ups maybe. Maybe not. But according to what a lot of people say, you probably will. We’ll be able to put them out. You may have some flare-ups next year, but eventually, it’s going to be gone. I mean, it’s going to be gone.
President Trump May 8, 2020

We think we’re going to have a vaccine in the pretty near future. And if we do, we’re going to really be a big step ahead. And if we don’t, we’re going to be like so many other cases, where you had a problem come in, it’ll go away — at some point, it’ll go away. It may flare up, and it may not flare up. We’ll have to see what happens.
President Trump May 15, 2020

So I think that’s — but even without that [a vaccine or therapeutics], you know, at some point this stuff goes away and it’s going away.
President Trump June 15, 2020

I always say, even without it [a vaccine], it goes away.
President Trump June 16, 2020

…if you look, the numbers are very minuscule compared to what it was. It’s dying out.
President Trump June 17, 2020

But I will tell you, we’re very close to a vaccine, and we’re very close to therapeutics, really good therapeutics. And — but even without that — I don’t even like to talk about that, because it’s fading away. It’s going to fade away.
President Trump June 17, 2020

And it is dying out. The numbers are starting to get very good.
President Trump June 18, 2020

And I think we are going to be very good with the coronavirus. I think that, at some point, that’s going to sort of just disappear, I hope.
President Trump July 1, 2020

I’ll be right eventually. I will be right eventually. You know I said, ‘It’s going to disappear.’ I’ll say it again. It’s going to disappear, and I’ll be right.
President Trump July 19, 2020

Well, the virus will disappear. It will disappear.
President Trump July 21, 2020

We’re gonna beat it, yeah. We’re going to beat it. And with time, you’re going to be it — time. You know, I say, it’s going to disappear. And they say, ‘Oh, that’s terrible.’ He said — well, it’s true. I mean, it’s going to disappear. Before it disappears, I think we can knock it out before it disappears.
President Trump July 22, 2020

This thing’s going away. It will go away like things go away…
President Trump August 5, 2020

It’s going away. No, it’ll go away like things go away. Absolutely. No question in my mind. It will go away. Hopefully sooner rather than later.
President Trump August 5, 2020

And we’re getting them [manufacturing jobs] even in a pandemic — which is disappearing; it’s going to disappear.
President Trump August 7, 2020

And frankly, you know, we’ve had a tremendous — a tremendous market, you and I have talked about that, the stock market. Think of it, we’re almost back to where we were, and we’re still in the pandemic, which will be going away, as I say, it’ll be going away. And they scream, how you can you say that? I said, because it’s gonna be going away.
President Trump August 13, 2020

…And the China Plague will fade.
President Trump August 17, 2020

And as soon as the plague is gone — we have vaccines coming, we have therapeutics coming, and it’s going to be gone. And it’s gonna be gone soon.
President Trump August 17, 2020

It’s all coming back so fast and you’ll see it, and the pandemic goes away. The vaccines are going to be, I believe, announced very soon.
President Trump August 24, 2020

Well, once you get to a certain number — you know, we use the word herd, right. Once you get to a certain number, it’s going to go away.
President Trump August 31, 2020

It is gonna disappear. It’s gonna disappear. I still say it.
President Trump September 15, 2020

But it’s going to disappear. It is disappearing. And vaccines are going to help, and the therapeutics are going to help a lot.
President Trump October 10, 2020

The vaccine will end the pandemic. But it’s ending anyway. I mean, they go crazy when I say it. It’s going to peter out and it’s going to end. But we’re going to help the end and we’re gonna make it a lot faster with the vaccine and with the therapeutics and frankly with the cures.
President Trump October 15, 2020

Even without the vaccine, the pandemic’s going to end. It’s gonna run its course. It’s gonna end. They’ll go crazy. He said ‘without the vaccine’ — watch, it’ll be a headline tomorrow. These people are crazy. No, it’s running its course.
President Trump October 16, 2020
 
Love owning you to this extent, that you even obsess over me with your sig line. Almost as cringy as Steelworth, Tim and Steeltime. Just can't keep me out of your heads. As the saying goes, I live there, rent free, 24/7. Damn, had no idea how deeply all this trauma has affected you. Hope things start looking up from here on. Life's too short to be this obsessed over a random stranger on a messageboard. Well, maybe not. Whatever turns you on, man. Yikes. Merry Christmas, Supe. 🤷‍♂️
LOL - **** off, Cuckboy. You're again assuming that you're some alpha when we all know you're not. you're the same little dipshit douche who ran away from the board when your political idols faulted and were not regaled as you so openly pined. I will commend you for giving a damn about politics in a foreign country, as I sure don't give a **** about what happens in Cucktardistan, Tibor.
 
btw - i'd list all the times that Biden said one thing or another about the WooFloo, but most of that would be plagiarizing.
 
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