I'm not going to say it's going to happen, but there was a game against New England in 2009 or 2010 when we had a lot of linebackers hurt (Woodley, Timmons, Harrison or something to that effect) and that was the first time in a bazillion years Lebeau played almost all dime defense against Brady and we pressed everyone and won pretty easily.
I think against New England it is pretty much a no brainer at this point we are going to play almost all nickel and probably a lot of dime as well. Not sure the Moats/Spence thing worked or they earned themselves more snaps.
I think you're going to see a lot of 3 DL, 2 OLB and 6 DB's. We might not play any inside linebackers at all. Dare them to run up the middle on us.