There were 11 seconds left when the pass was incomplete. Assuming that the pass was completed, Muth most likely would not have gone down and been touched immediately. This means that time is running out quickly. The play looked to be about 13 yards, to the 47. He has to try and get at least to the 38 for a 55yd FG attempt. I would guess that takes another 4-6 seconds to get the yardage and down by contact. That means that EVERYONE has to get 22yds down field and set so Wilson can spike the ball, all in 5-7 seconds. No way in heil does that happen. Pickens and his bad attitude would not have done it, let alone in that limited time.
The pass across the middle by Smith/Wilson doomed the very slight chance they had. Now if they had done it on 3rd down, maybe they have a shot. The only shot they had was an out route to get the 1st and out of bounds.
Across the middle, Muth had to take it the distance. The kid is not built for a 60yd TD through the middle of the Defense. He would have never made it.